Overall, we are most impressed with the serum’s ability to clear out our pores quickly without causing any dryness or irritation — two common, dreaded retinol side effects. Both of us would happily incorporate this serum into our nightly routine, and have been using it alongside our usual suite of essentials, such as hyaluronic acid serums, face creams with niacinamide and ceramides, and of course, our SPF. Sun protection is a crucial step since retinol makes your skin more sensitive to sunlight.